abstract：CONCLUSION:Our findings suggest that there exists a Na(+) transport system in the cochlea consisting of SGK1, Nedd4 isoforms and ENaC, which may work in concert to transport Na(+) and to maintain homeostasis in the inner ear as they do in other tight epithelia. OBJECTIVES:It has been well demonstrated that the epithel...

journal_title：Acta oto-laryngologica

authors： Zhong SX,Liu ZH

更新日期：2009-09-01 00:00:00

abstract：CONCLUSIONS:The expression of phosphorylcholine (ChoP) in the surface of nontypeable Haemophilus influenzae (NTHi) is an important factor in the pathogenesis of persistent otitis media with effusion (OME) in humans. OBJECTIVES:Lipooligosaccharide (LOS) in NTHi undergoes phase variation in expression of the ChoP epitop...

journal_title：Acta oto-laryngologica

authors： Fujita K,Hirano T,Kodama S,Suzuki M

更新日期：2009-08-01 00:00:00

abstract：CONCLUSION:Cochlear implant (CI) recipients' performance of lexical tone identification and consonant recognition can be enhanced by providing greater spectral details. OBJECTIVE:To evaluate the effects of increasing the number of total spectral channels on the lexical tone identification and consonant recognition by ...

journal_title：Acta oto-laryngologica

authors： Lin YS,Lu HP,Hung SC,Chang CP

更新日期：2009-06-01 00:00:00

abstract：CONCLUSIONS:A large series confirmation may suggest elective neck dissection in cN0 MASPIN-negative oral squamous cell carcinomas (SCCs). Re-activated nuclear MASPIN in association with anti-angiogenic or cytotoxic drugs may be extremely effective in the treatment of laryngeal SCC. OBJECTIVES:MASPIN is a serpin showin...

journal_title：Acta oto-laryngologica

authors： Marioni G,Staffieri C,Staffieri A,De Filippis C,Blandamura S

更新日期：2009-05-01 00:00:00

abstract：CONCLUSION:After conventional curette adenoidectomy, a significant mass of residual adenoid tissue is observed in about 50% of the cases. The combined approach of conventional curette and endoscopic adenoidectomy with microdebrider assures a complete and accurate removal of the mass. It is an effective and safe method ...

journal_title：Acta oto-laryngologica

authors： Pagella F,Matti E,Colombo A,Giourgos G,Mira E

更新日期：2009-05-01 00:00:00

abstract：CONCLUSION:There are two modalities of dual electrode stimulation: a shifting, continuous excitation, which is the desired effect, and a split excitation with considerable variation in loudness. The first one most likely occurs in the basal turn, with adjacent contacts, stimulated simultaneously rather than sequentiall...

journal_title：Acta oto-laryngologica

authors： Frijns JH,Kalkman RK,Vanpoucke FJ,Bongers JS,Briaire JJ

更新日期：2009-04-01 00:00:00

abstract：CONCLUSION:The incidence of new cases of Meniere's disease (MD) in elderly patients aged 60 years or more was found to have increased over time after correction for age distribution in the overall population. Job- and care-related fatigue may be involved in the recent increase in elderly-onset cases because physical an...

journal_title：Acta oto-laryngologica

authors： Shojaku H,Watanabe Y,Yagi T,Takahashi M,Takeda T,Ikezono T,Ito J,Kubo T,Suzuki M,Takumida M,Takeda N,Furuya N,Yamashita H,Peripheral Vestibular Disorder Research Committee of Japan.

更新日期：2009-02-01 00:00:00

abstract：CONCLUSION:A very low dose of dexamethasone (DEX) was as equally as sufficient as a pharmacological dose to decrease eosinophil inflammation in airways and bone marrow. The timing of DEX treatment in relation to allergen challenge was strongly decisive for the outcome of the inflammatory response. OBJECTIVES:We aimed ...

journal_title：Acta oto-laryngologica

authors： Georén SK,Tcacencu I,Wikström AC,Stierna P

更新日期：2009-02-01 00:00:00

abstract：CONCLUSION:Abnormal caloric and vestibular evoked myogenic potential (VEMP) responses are frequently encountered with a large cerebellopontine angle (CPA) schwannoma, while normal caloric responses and abnormal VEMPs are noted with a large CPA meningioma. This difference may possibly exist because schwannoma causes ves...

journal_title：Acta oto-laryngologica

authors： Hu YF,Cheng PW,Young YH

更新日期：2009-02-01 00:00:00

abstract：CONCLUSION:The endoscopic approaches developed for the treatment of the chordomas according to the different clival location provide the possibility for more complete tumor resection with maximal preservation of anatomic structures and reduction of the overall incidence of complications. OBJECTIVE:The endoscope has re...

journal_title：Acta oto-laryngologica

authors： Hong Jiang W,Ping Zhao S,Hai Xie Z,Zhang H,Zhang J,Yun Xiao J

更新日期：2009-01-01 00:00:00

abstract：CONCLUSION:The results of this study suggest that treatment with radical scavengers has the potential to become an effective new therapy for age-related hearing loss. OBJECTIVE:To assess the efficacy of treatment with radical scavengers for age-related hearing loss. SUBJECTS AND METHODS:Rebamipide (300 mg/day), alpha...

journal_title：Acta oto-laryngologica

authors： Takumida M,Anniko M

更新日期：2009-01-01 00:00:00

abstract：CONCLUSION:Our results suggest that patients with migraine or tension-type headache have subclinical deviations of the subjective visual vertical, which may be associated with their subjective imbalance. OBJECTIVES:Patients affected by migraine or tension-type headache often complain of unsteadiness. However, they rar...

journal_title：Acta oto-laryngologica

authors： Asai M,Aoki M,Hayashi H,Yamada N,Mizuta K,Ito Y

更新日期：2009-01-01 00:00:00

abstract：CONCLUSIONS:In addition to the correlation of transforming growth factor (TGF)-beta1 levels to the radiation toxicity, both Epstein-Barr virus (EBV) infection and postoperative status play roles in the change in plasma TGF-beta1 levels in patients with head and neck cancers. OBJECTIVES:To assess the parameters involve...

journal_title：Acta oto-laryngologica

authors： Chen HW,Yang SF,Chang YC,Wang TY,Chen YJ,Hwang JJ

更新日期：2008-10-01 00:00:00

abstract：CONCLUSION:GABA-mediated inhibition is responsible for the duration tuning in the inferior colliculus (IC) of guinea pigs, a non-echo-locating mammal. Duration tuning in this species is better demonstrated in an appropriate short time window. OBJECTIVES:To investigate the role of GABA-mediated inhibition in duration t...

journal_title：Acta oto-laryngologica

authors： Yin S,Chen Z,Feng Y,Wang J

更新日期：2008-10-01 00:00:00

abstract：CONCLUSION:The existence of patients with positive non-sentinel node indicates a risk of misdiagnosis of metastasis in oropharyngeal and oral cancer. OBJECTIVES:We attempted to confirm the usefulness of sentinel lymph node biopsy (SLNB) in oropharyngeal and oral cavity cancer to detect clinically occult metastases. P...

journal_title：Acta oto-laryngologica

authors： Santaolalla F,Sanchez JM,Ereño C,Gonzalez A,Rodriguez ML,Sanchez A,Martinez A

更新日期：2008-10-01 00:00:00

abstract：CONCLUSION:Chronic subjective dizziness (CSD) is frequent and affects twice as many women as men. Anxiety is a strong predisposing factor. The pathophysiologic concept of this disorder assumes that balance function and emotion share common neurologic pathways, which might explain that the balance disorder can provoke f...

journal_title：Acta oto-laryngologica

authors： Odman M,Maire R

更新日期：2008-10-01 00:00:00

abstract：CONCLUSION:The aetiology of Zenker's diverticulum is likely to be multifactorial. The geographical and racial variation in the prevalence and the rare familial cases suggest that genetic predisposition might have a role in the pathogenesis. The mode of inheritance in the rare possible familial cases seems to be autosom...

journal_title：Acta oto-laryngologica

authors： Klockars T,Sihvo E,Mäkitie A

更新日期：2008-09-01 00:00:00

abstract：CONCLUSIONS:In our study setting nitrous oxide (N(2)O) did not show any clinical benefit in discomfort experienced when applying local anesthesia for nasal operations. Further studies with longer inhalation times are needed to elucidate the role of N(2)O in application of local anesthesia in nasal surgery. OBJECTIVES:...

journal_title：Acta oto-laryngologica

authors： Starck M,Tarkkila P,Mäkitie AA,Ylikoski JS,Bäck LJ

更新日期：2008-07-01 00:00:00

abstract：CONCLUSION:Speech thresholds measured using Cantonese Hearing in Noise Test (CHINT) and cortical evoked response audiometry (CERA) thresholds were highly correlated with pure-tone behavioral results. Both tests are considered to provide good estimates of hearing thresholds and can be employed to confirm the degree of h...

journal_title：Acta oto-laryngologica

authors： Wong LL,Cheung C,Wong EC

更新日期：2008-06-01 00:00:00

abstract：:It is known that 15-20% of oropharyngeal carcinomas develop distant metastases that involve most commonly lung, liver and bone. Clival metastasis from oropharyngeal squamous cell carcinoma has not been previously reported in the English literature. We describe the rare occurrence of clival metastasis from tonsillar ca...

journal_title：Acta oto-laryngologica

authors： Marchese-Ragona R,Maria Ferraro S,Marioni G,Staffieri C,Manara R,Restivo DA,Staffieri A

更新日期：2008-06-01 00:00:00

abstract：CONCLUSION:The study showed that surgery in the maxillary sinus can affect its development. OBJECTIVE:To quantitatively evaluate the long-term impact of sinus surgery on its development in the rabbit. MATERIALS AND METHODS:This was an experimental study performed at an academic tertiary medical center using 20 4-week...

journal_title：Acta oto-laryngologica

authors： Bahadir O,Bahadir A,Kosucu P,Livaoglu M

更新日期：2008-05-01 00:00:00

abstract：CONCLUSIONS:We conclude that: (1) among several cues examined, the monaural cue of direct-to-reverberant (D/R) ratio in the ipsilateral ear provides the most information about sound-source distance; (2) interaural level difference (ILD) provides less information about sound-source distance; and (3) a comprehensive theo...

journal_title：Acta oto-laryngologica

authors： Kim DO,Moiseff A,Turner JB,Gull J

更新日期：2008-04-01 00:00:00

abstract：CONCLUSION:L-N-Acetylcysteine (L-NAC) significantly reduced reactive oxygen species (ROS) generation and cochlear cell apoptosis after irradiation. The safe and effective use of L-NAC in reducing radiation-induced sensorineural hearing loss (SNHL) should be verified by further in vivo studies. OBJECTIVES:Radiation-ind...

journal_title：Acta oto-laryngologica

authors： Low WK,Sun L,Tan MG,Chua AW,Wang DY

更新日期：2008-04-01 00:00:00

abstract：CONCLUSION:Videomicroscopy with subpixel analysis is an excellent system for quantification of outer hair cell (OHC) movements. The resolution of a few nanometers is accurate enough to show induced differences of electromotility. OBJECTIVE:Electromotility of OHCs is a voltage-dependent process resulting from a membran...

journal_title：Acta oto-laryngologica

authors： Canis M,Ortner M,Olzowy B,Jahn K,Strupp M,Hemmert W,Berghaus A,Suckfuell M

更新日期：2008-03-01 00:00:00

abstract：:The existence of primary thyroid sarcomas represents a contentious issue. Some authors believe that thyroid sarcomas are, in fact, anaplastic carcinomas with sarcomatous (spindle cell) features. From the standpoint of treatment and prognosis, the histogenesis of thyroid 'sarcomas' is academic, because these tumors, ir...

journal_title：Acta oto-laryngologica

authors： Mansouri H,Gaye M,Errihani H,Kettani F,Gueddari BE

更新日期：2008-03-01 00:00:00

abstract：CONCLUSIONS:Homeostasis of endolymph volume is a complex mechanism, in which the endolymphatic sac (ES) may play an important role. OBJECTIVES:To elucidate the effect of acute endolymphatic hydrops (EH) on the ES and to gain further information about the volume and pressure regulative function of the ES. MATERIALS AN...

journal_title：Acta oto-laryngologica

authors： Akagi N,Takumida M,Anniko M

更新日期：2008-03-01 00:00:00

abstract：CONCLUSION:A new murine model for the study of Ménière's disease has been developed by treatment with both lipopolysaccharide (LPS) and aldosterone. Induction of vestibular dysfunction in the hydropic animal model may entail additional stress such as reduced inner ear blood flow, and sudden acute changes in endolymph v...

journal_title：Acta oto-laryngologica

authors： Takumida M,Akagi N,Anniko M

更新日期：2008-03-01 00:00:00

abstract：CONCLUSION:Computed tomography (CT) in nasal polyposis (NP) patients has three functions before any treatment. CT provides objective evidence of the disease and precise topography of the disease, and is an indicator of the disease severity. After functional endoscopic sinus surgery (FESS), CT is an indicator of the res...

journal_title：Acta oto-laryngologica

authors： Bonfils P,Tavernier L,Abdel Rahman H,Mimoun M,Malinvaud D

更新日期：2008-03-01 00:00:00

abstract：CONCLUSIONS:Available multichannel cochlear implants (CIs) provide effective tinnitus suppression. More sophisticated speech strategies are more effective than analogue or slow strategies. The mechanisms by which tinnitus is suppressed by CIs are unclear; however, both acoustic masking and reorganization of the right a...

journal_title：Acta oto-laryngologica

authors： Quaranta N,Fernandez-Vega S,D'elia C,Filipo R,Quaranta A

更新日期：2008-02-01 00:00:00

abstract：CONCLUSION:Although sentinel lymph node (SLN) biopsy is not yet validated for clinical use to replace elective neck dissection in patients with oral squamous cell carcinoma, it can be recommended for patients who do not fulfil the criteria for elective neck treatment according to current treatment protocols. OBJECTIVE...

journal_title：Acta oto-laryngologica

authors： Keski-Säntti H,Kontio R,Leivo I,Törnwall J,Mätzke S,Mäkitie AA,Atula T

更新日期：2008-01-01 00:00:00

abstract：CONCLUSIONS:The facial nerve courses shown by preoperative CT imaging coincide with the surgical findings in most congenital aural atresia cases. CT scanning is critical in evaluation of a patient's candidacy for atresia surgery. OBJECTIVES:To evaluate the diagnostic value of preoperative CT scanning of the facial ner...

journal_title：Acta oto-laryngologica

authors： Yu Z,Han D,Gong S,Wang Z,Dai H,Zhao S,Zheng Y,Leng T

更新日期：2008-01-01 00:00:00

abstract：CONCLUSIONS:The underlying pathophysiological mechanisms of the posterior nasal nerve (PNN) resection involved the suppression of the secretogogue motor and the inhibition of neurogenic inflammation induced by parasympathetic and sensory denervation. OBJECTIVE:The study was designed to clarify the underlying mechanism...

journal_title：Acta oto-laryngologica

authors： Ikeda K,Yokoi H,Saito T,Kawano K,Yao T,Furukawa M

更新日期：2008-01-01 00:00:00

abstract：CONCLUSION:Coexistent migraine affects relevant clinical features of patients with Ménière's disease (MD). OBJECTIVE:Epidemiological studies have shown an association between migraine and MD. We sought to determine whether the coexistence of migraine affects any clinical features in patients with MD. PATIENTS AND MET...

journal_title：Acta oto-laryngologica

authors： Cha YH,Brodsky J,Ishiyama G,Sabatti C,Baloh RW

更新日期：2007-12-01 00:00:00

abstract：CONCLUSION:Salivary gland diseases should be handled with a high index of suspicion. Although an inference could be drawn it is not clear from this study if primary head and neck cancers (HNCs) have a significant association with HIV/AIDS. OBJECTIVE:HIV/AIDS manifestations and malignancies do occur in the head and nec...

journal_title：Acta oto-laryngologica

authors： Nwaorgu O,Kokong D,Onakoya P,Adoga S,Ibekwe T

更新日期：2007-11-01 00:00:00

abstract：CONCLUSIONS:The presented results add further support to the observation that laser microsurgery is the preferential surgical treatment for recurrent respiratory papillomatosis (RRP). A meticulous follow-up for early recognition of local recurrence and malignant transformation is recommended. OBJECTIVES:Endoscopic mic...

journal_title：Acta oto-laryngologica

authors： Preuss SF,Klussmann JP,Jungehulsing M,Eckel HE,Guntinas-Lichius O,Damm M

更新日期：2007-11-01 00:00:00

abstract：CONCLUSIONS:Concurrent chemoradiotherapy with carboplatin and uracil-f tegafur (UFT) seems to be a promising and appropriate regimen for patients with poor performance status (PS) with locally advanced squamous cell carcinoma of the head and neck (SCCHN). OBJECTIVE:We designed a regimen based on divided low-dose admin...

journal_title：Acta oto-laryngologica

authors： Katori H,Tsukuda M,Taguchi T

更新日期：2007-10-01 00:00:00

abstract：:This report shows the changes that occurred in consecutive audiograms of a patient who underwent chemotherapy and radiotherapy for nasopharyngeal cancer and the histopathological examination of the temporal bones. Both conductive and sensorineural hearing loss developed, but followed different modes of progression. In...

journal_title：Acta oto-laryngologica

authors： Asenov DR,Kaga K,Tsuzuku T

更新日期：2007-10-01 00:00:00

abstract：CONCLUSIONS:Thorough otomicroscopical examination of the tympanic membrane in acute otitis media (AOM) might distinguish AOM episodes caused by different bacteria. It thus might be a way to select appropriate treatment for each patient without raising the number of dangerous complications. OBJECTIVES:The aim of this s...

journal_title：Acta oto-laryngologica

authors： Foglé-Hansson M,White P,Hermansson A

更新日期：2007-09-01 00:00:00

abstract：CONCLUSIONS:The incidence of tonsillar cancer in Sweden is increasing, particularly among men. Risk factors other than smoking may have contributed to the observed secular trend in men. In women, however, smoking can be a part of the explanation. Further studies to look at changes in other environmental factors, such a...

journal_title：Acta oto-laryngologica

authors： Hammarstedt L,Dahlstrand H,Lindquist D,Onelöv L,Ryott M,Luo J,Dalianis T,Ye W,Munck-Wikland E

更新日期：2007-09-01 00:00:00

abstract：CONCLUSIONS:The most likely cause of lesions with an absence of the long process of the incus was congenital origin because many cases were associated with the stapedial anomaly. However, the possibility of a potential inflammation of this lesion could not be completely excluded, especially in cases with only an absenc...

journal_title：Acta oto-laryngologica

authors： Park K,Choung YH,Shin YR,Hong SP

更新日期：2007-08-01 00:00:00